Hemodynamic Response to Interictal Epileptiform Discharges Addressed by Personalized EEG-fNIRS Recordings

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Hemodynamic Response to Interictal Epileptiform Discharges Addressed by Personalized EEG-fNIRS Recordings

OBJECTIVE We aimed at studying the hemodynamic response (HR) to Interictal Epileptic Discharges (IEDs) using patient-specific and prolonged simultaneous ElectroEncephaloGraphy (EEG) and functional Near InfraRed Spectroscopy (fNIRS) recordings. METHODS The epileptic generator was localized using Magnetoencephalography source imaging. fNIRS montage was tailored for each patient, using an algori...

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fNIRS-EEG study of focal interictal epileptiform discharges.

Functional near-infrared spectroscopy (fNIRS) acquired with electroencephalography (EEG) is a relatively new non-invasive neuroimaging technique with potential for long term monitoring of the epileptic brain. Simultaneous EEG-fNIRS recording allows the spatio-temporal reconstruction of the hemodynamic response in terms of the concentration changes in oxy-hemoglobin (HbO) and deoxy-hemoglobin (H...

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Detection of Interictal Epileptiform Discharges in Eeg

The diagnosis of epilepsy heavily depends on the detection of epileptiform discharges in interictal EEG, the EEG in between two seizures. By visual analysis a physician wants to detect these epileptiform discharges (spikes). Due to the wide variety of morphologies of epileptiform discharges, and their similarity to waves that are part of normal EEG or to artifacts, this detection is far from st...

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The BOLD response to interictal epileptiform discharges.

We studied single-event and average BOLD responses to EEG interictal epileptic discharges (IEDs) in four patients with focal epilepsy, using continuous EEG-fMRI during 80-min sessions. The detection of activated areas was performed by comparing the BOLD signal at each voxel to a model of the expected signal. Since little is known about the BOLD response to IEDs, we modeled it with the response ...

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Interictal Epileptiform Discharges

EEG remains the primary technique in the diagnosis, characterization, and localization of partial seizures. This review examines the significance and character of interictal epileptiform abnormailites, periodic lateralized epileptiform discharges, and ictal patterns in patients with partial epilepsy. Interictal epileptiform discharges are common and assist in the diagnosis and localization of p...

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ژورنال

عنوان ژورنال: Frontiers in Neuroscience

سال: 2016

ISSN: 1662-453X

DOI: 10.3389/fnins.2016.00102